Project Details
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Gentransfer in mesenchymale Stammzellen zur Knorpelreparation - Modulation der hypertrophen Chondrogenese und in vivo Applikation

Subject Area Orthopaedics, Traumatology, Reconstructive Surgery
Term from 2006 to 2012
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 21827687
 
Final Report Year 2012

Final Report Abstract

No abstract available

Publications

  • Major biological obstacles for persistent cell-based regeneration of articular cartilage. Arthritis Research & Therapy, Vol. 9. 2007, Issue 3: 213.
    Steinert A.F., Ghivizzani S.C., Rethwilm A., Tuan R.S., Evans C.H., Nöth U.
    (See online at https://dx.doi.org/10.1186/ar2195)
  • Concepts in gene therapy for cartilage repair. Injury 2008; 39S1: S97-113. [1F:1.509] (Anlage 2) Injury, Vol. 39. 2008, Issue 1, Supplement, pp. 97–113.
    Steinert A.F., Nöth U., Tuan R.S.
    (See online at https://dx.doi.org/10.1016/j.injury.2008.01.034)
  • Technology Insight: adult mesenchymal stem cells for osteoarthritis therapy. Nature Clinical Practice Rheumatology, Vol. 4. 2008, Issue 7, pp. 371-380.
    Nöth U., Steinert A.F., Tuan R.S.
    (See online at https://dx.doi.org/10.1038/ncprheum0816)
  • Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer. Tissue Engineering Part A, Vol. 15. 2009, Issue 5, pp. 1127-1139.
    Steinert A.F., Palmer G.D., Gouze E., Gouze J.N., Pilapil C., Nöth U., Evans C.H., Ghivizzani S.C.
    (See online at https://dx.doi.org/10.1089/ten.tea.2007.0252)
  • Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer. Arthritis Research & Therapy, Vol. 11.2009: R148.
    Steinert A.F., Proffen B., Kunz M., Hendrich C., Ghivizzani S., Nöth U., Eulert J., Evans C.
    (See online at https://dx.doi.org/10.1186/ar2822)
  • Cell Delivery Therapeutics for Musculoskeletal Regeneration. Advanced Drug Delivery Reviews, Vol. 62. 2010, Issues 7–8, pp. 765–783.
    Nöth U., Rackwitz L., Steinert A., Tuan R.
    (See online at https://dx.doi.org/10.1016/j.addr.2010.04.004)
  • Concise Review: The Clinical Application of Mesenchymal Stem Cells for Musculoskeletal Regeneration: Current Status and Perspectives. Stem Cells Translational Medicine, Vol. 1. 2012, Number 3, pp. 237-247.
    Steinert A.F., Rackwitz L., Gilbert F., Nöth U., Tuan R.
    (See online at https://doi.org/10.5966/sctm.2011-0036)
  • Indian hedgehog gene transfer is a chondrogenic inducer of human mesenchymal stem cells. Arthritis Research & Therapy, Vol. 14. 2012: R168.
    Steinert A.F., Weissenberger M., Kunz M., Gilbert F., Ghivizzani S.C., Göbel S., Jakob F., Nöth U., Rudert M.
    (See online at https://doi.org/10.1186/ar3921)
 
 

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