Project Details
Projekt
Analysis of APR Dimerization in vivo and the impact on neurodegeneration in Alzheimer's Disease
Applicant
Dr. Simone Eggert
Subject Area
Molecular Biology and Physiology of Neurons and Glial Cells
Term
from 2006 to 2007
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 22012210
Final Report Year
2008
Final Report Abstract
Taken together, we established a new approach for APP dimerization with the FKBP-AP20187 system, thereby revealing a decrease of Aß production after dimerization, which is of major importance, since Aß is one of the key players in Alzheimer's Disease.
