Cytoskeletal interactions in axonal transport

• Applicant: Professor Dr. Eckhard Mandelkow
• Subject Area: Cell Biology
• Term: from 2006 to 2015
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 14023866

Final Report Abstract

No abstract available

Publications

• (2009). Structures of kinesin motor proteins. Cell Mot. Cytoskel. 66, 958-966
  Marx, A., Hoenger, A., Mandelkow, E.
  
• (2010). Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines. J. Neurosci. 30, 11938-11950
  Zempel H, Thies E, Mandelkow E, Mandelkow EM
  
• (2010). Structure of the motor protein kinesin. In: "Research with Synchrotron Radiation", J. Falta & T. Möller, Eds. Vieweg & Teubner Verlag, p. 418-428
  Sack, S., Marx, A., Mandelkow, E.
  
• (2011). Microtubule affinity regulating kinase (MARK) activity in living neurons examined by a genetically encoded FRET/FLIM based biosensor: Inhibitors with therapeutic potential. J. Biol. Chem 286, 41711-41722
  Timm, T., von Kries, J. P., Li, X., Zempel, H., Mandelkow, E., Mandelkow, E. M.
  
• (2011). Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration. EMBO J. 30, 4825-4837
  Li, X., Kumar, Y., Zempel,, H., Mandelkow, E. M., Biernat, J., Mandelkow, E.
  
• (2012). Tau protein diffuses along the microtubule lattice. J. Biol. Chem. 287, 38559-38568
  Hinrichs, M.A., Jalal, A., Brenner, B., Kumar, S., Mandelkow, E., Scholz, T.