Deep-Sequencing / Bioinformatics (Z01)

• Subject Area: General Genetics and Functional Genome Biology
• Term: from 2012 to 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 192904750

A molecular understanding of disease mechanisms requires a global approach to the study of chromatin states and gene regulation. We will provide our infrastructure and expertise with deep-sequencing technologies to generate genome-wide maps of epigenetic modifications in various cell types. A dedicated data management centre will be further developed to facilitate access, visualization and routine analysis of genome-wide data. Our group will also offer regular training and help to improve the capacity for epigenetic research towards the development of potential epigenetic therapies.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 992: Medical Epigenetics (MEDEP) - From Basic Mechanisms to Clinical Applications
• Major Instrumentation: Oxford nanopore GridlON X5
• Instrumentation Group: 3150 DNA-Sequenzer
• Applicant Institution: Albert-Ludwigs-Universität Freiburg
• Project Heads: Professor Dr. Rolf Backofen; Dr. Thomas Manke