Connecting sulfur transfer pathways for molybdenum cofactor biosynthesis and tRNA thiolation in humans

Applicant Professorin Dr. Silke Leimkühler

Subject Area Biochemistry

Term from 2013 to 2021

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 230491980

Final Report Year 2022

Final Report Abstract

No abstract available

(2014) Characterization and Interaxtion Studies of Two Isoforms of the Dual Localized 3-Mercaptopyruvate Sulfurtransferase TUM1 from Humans, J. Biol. Chem. 289:34543-56
Fräsdorf, B., Radon, C., Leimkühler, S.
(See online at https://doi.org/10.1074/jbc.m114.605733)
Shared Sulfur Mobilization Routes for tRNA Thiolation and Molybdenum Cofactor Biosynthesis in Prokaryotes and Eukaryotes. (2017) Biomolecules., 7(1)
Leimkühler, S., Bühning, M., Beilschmidt, L.
(See online at https://doi.org/10.3390/biom7010005)
(2019) Analysis of the Cellular Roles of MOCS3 Identifies a MOCS3-Independent Localization of NFS1 at the Tips of the Centrosome. Biochemistry 58:1786-1798
Neukranz Y, Kotter A, Beilschmidt L, Marelja Z, Helm M, Gräf R, Leimkühler S.
(See online at https://doi.org/10.1021/acs.biochem.8b01160)