Connecting sulfur transfer pathways for molybdenum cofactor biosynthesis and tRNA thiolation in humans

• Applicant: Professorin Dr. Silke Leimkühler
• Subject Area: Biochemistry
• Term: from 2013 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 230491980

• Final Report Year: 2022

Final Report Abstract

No abstract available

Publications

• (2014) Characterization and Interaxtion Studies of Two Isoforms of the Dual Localized 3-Mercaptopyruvate Sulfurtransferase TUM1 from Humans, J. Biol. Chem. 289:34543-56
  Fräsdorf, B., Radon, C., Leimkühler, S.
  
• Shared Sulfur Mobilization Routes for tRNA Thiolation and Molybdenum Cofactor Biosynthesis in Prokaryotes and Eukaryotes. (2017) Biomolecules., 7(1)
  Leimkühler, S., Bühning, M., Beilschmidt, L.
  
• (2019) Analysis of the Cellular Roles of MOCS3 Identifies a MOCS3-Independent Localization of NFS1 at the Tips of the Centrosome. Biochemistry 58:1786-1798
  Neukranz Y, Kotter A, Beilschmidt L, Marelja Z, Helm M, Gräf R, Leimkühler S.