Vitamin D regulation of the skin innate immune response (B13)

• Subject Area: Dermatology
• Term: from 2013 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 73111208

The cooperative response of immune cells is crucial to ensure tissue homeostasis by promoting an appropriate inflammatory and antimicrobial host response. In this project we will analyse the collaboration of innate immune cells in the skin during the inflammatory and antimicrobial host response against intracellular pathogens. In particular, we want to understand the role of vitamin D hormone in regulating these interactions. In the long term such studies could be of importance for the design of novel host-directed therapies.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 829: Molecular Mechanisms Regulating Skin Homeostasis
• Applicant Institution: Universität zu Köln
• Project Head: Professor Dr. Mario Fabri