Heisenberg Professorship in Hematology/Oncology "Immune-regulation and tumor immunology"

• Applicant: Professor Dr. Robert Zeiser
• Subject Area: Hematology, Oncology
• Term: from 2013 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 235287988

• Final Report Year: 2018

No abstract available

Publications

• The NIrp3 inflammasome regulates acute graft-versus-host disease. Journal of Experimental Medicine, Vol. 210. 2013, Issue 10, pp. 1899–1910.
  Jankovic, Dragana; Ganesan, Jayanthi; Bscheider, Michael; Stickel, Natalie; Weber, Felix C.; Guarda, Greta; Follo, Marie; Pfeifer, Dietmar; Tardivel, Aubry; Ludigs, Kristina; Bouazzaoui, Abdellatif; Kerl, Katrin; Fischer, Julius C.; Haas, Tobias; Schmitt-Gräff, Annette; Manoharan, Anand; Müller, Leonard; Finke, Jürgen; Martin, Stefan F.; ... & Zeiser, Robert
  
• Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance GvHD via tissue damage. Nature Medicine, Vol. 20. 2014, pp. 648–654.
  Schwab, Lukas; Goroncy, Luise; Palaniyandi, Senthilnathan; Gautam, Sanjivan; Triantafyllopoulou, Antigoni; Mocsai, Attila; Reichardt, Wilfried; Karlsson, Fridrik J; Radhakrishnan, Sabarinath V; Hanke, Kathrin; Schmitt-Graeff, Annette; Freudenberg, Marina; von Loewenich, Friederike D; Wolf, Philipp; Leonhardt, Franziska; Baxan, Nicoleta; Pfeifer, Dietmar; Schmah, Oliver; Schönle, Anne; ... & Zeiser, Robert
  
• Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into allereactive T cells. Blood, Vol. 127. 2016, Issue 15 pp. 1930–1939.
  Schönle, Anne; Hartl, Frederike A.; Mentzel, Jan; Nöltner, Theresa; Rauch, Katharina S.; Prestipino, Alessandro; Wohlfeil, Sebastian A.; Apostolova, Petya; Hechinger, Anne-Kathrin; Melchinger, Wolfgang; Fehrenbach, Kerstin; Guadamillas, Marta C.; Follo, Marie; Prinz, Gabriele; Ruess, Ann-Katrin; Pfeifer, Dietmar; Angel del Pozo, Miguel; Schmitt-Graeff, Annette; Duyster, Justus; ... & Zeiser, Robert
  
• Acute Graft-versus-Host Disease — Biologic Process, Prevention, and Therapy. The New England Journal of Medicine, Vol. 377. 2017, Issue 22, pp. 2167-2179.
  Zeiser, Robert & Blazar, Bruce R.
  
• MicroRNA-146a reduces MHC-II expression via targeting JAK/STAT signaling in dendritic cells after stem cell transplantation. Leukemia, Vol. 31. 2017, Issue 12, pp. 2732–2741.
  Stickel, N.; Hanke, K.; Marschner, D.; Prinz, G.; Köhler, M.; Melchinger, W.; Pfeifer, D.; Schmitt-Graeff, A.; Brummer, T.; Heine, A.; Brossart, P.; Wolf, D.; von Bubnoff, N.; Finke, J.; Duyster, J.; Ferrara, J.; Salzer, U. & Zeiser, R.
  
• Neutrophils provide cellular communication between ileum and mesenteric lymph nodes at graft-versus-host disease onset. Blood, Vol. 131. 2018, Issue 16, pp. 1858–1869.
  Hülsdünker, Jan; Ottmüller, Katja J.; Neeff, Hannes P.; Koyama, Motoko; Gao, Zhan; Thomas, Oliver S.; Follo, Marie; Al-Ahmad, Ali; Prinz, Gabriele; Duquesne, Sandra; Dierbach, Heide; Kirschnek, Susanne; Lämmermann, Tim; Blaser, Martin J.; Fife, Brian T.; Blazar, Bruce R.; Beilhack, Andreas; Hill, Geoffrey R.; Häcker, Georg; ... & Zeiser, Robert