Synthetic control of morphology and function in peptide based carrier systems (A06)

• Subject Area: Preparatory and Physical Chemistry of Polymers
• Term: from 2013 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 213555243

This project aims to control morphology and function of brush-like peptidic carriers, which are either derived from living polymerization or result from (further processed) natural monodisperse peptides. In addition, peptide based targeting units are modified to allow selective ligation. In combination this project aims at the preparation of systems to study, how morphology (rod or sphere like structures) and/or the ligation of antibodies modify the interaction of the carriers with immune cells.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1066: Nano-Dimensional Polymer Therapeutics for Tumour Therapy
• Applicant Institution: Johannes Gutenberg-Universität Mainz
• Co-Applicant Institution: Max-Planck-Institut für Polymerforschung
• Project Heads: Professor Dr. Matthias Barz; Professorin Dr. Tanja Weil