Multimodale and multiscalar in-vivo imaging of biodistribution and the efficiency of immunotherapy (Q03)

• Subject Area: Medical Physics, Biomedical Technology
• Term: from 2013 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 213555243

This project aims at in vivo imaging of the biodistribution of nanodimensional carriers on different length scales (from organ to cellular assembly) by PET- and optical methods. It is thereby the intention to validate fluorescence imaging against the quantitative PET method. In addition, methods to visualize the activation of the immune system (immuno-imaging) as result of the immunotherapy will be developed.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1066: Nano-Dimensional Polymer Therapeutics for Tumour Therapy
• Applicant Institution: Johannes Gutenberg-Universität Mainz
• Co-Applicant Institution: Rheinisch-Westfälische Technische Hochschule Aachen
• Project Heads: Professor Dr. Twan Lammers; Professor Dr. Matthias Miederer, Ph.D.; Professor Dr. Frank Rösch