Project Details
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Konfokales Spinning Disc Laserscanning-Mikroskop mit Inkubationseinheit für Live Cell Imaging

Subject Area Basic Research in Biology and Medicine
Term Funded in 2013
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 248122450
 
Final Report Year 2017

Final Report Abstract

Das wird Gerät intensiv innerhalb des SFB 1181 „Resolution in Inflammation“ genutzt. Die drei Hauptforschungsschwerpunkte sind: Checkpoint A: Cellular mechanisms controlling the switch from pro-inflammatory to antiinflammatory cytokine responses during the resolution phase of inflammation. Checkpoint B: Processes shifting lymphocyte responses towards an anti-inflammatory pattern. Checkpoint C: Contribution of cell death and reprogramming of resident tissue cells and immune cells to resolution of inflammation and repair. 1) How does C. burnetii spread? 2) What role does the host cell intermediate filament vimentin plays for the stability of the C. burnetii-containing vacuole (CCV). OICE hat in den letzten 15 Monaten Jahr organoide Kulturen verschiedenster Herkunft etabliert und darüber hinaus auch Methoden entwickelt, um die Organoide in Kultur ortsfest zu halten. Untersuchungen an myeloid-derived suppressor cells (MO-MDSCs).

Publications

  • A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function, Cell Metabolism
    Kälin S. et al.
    (See online at https://doi.org/10.1016/j.cmet.2017.08.008)
  • Impaired Transmigration of Myeloid-Derived Suppressor Cells across Human Sinusoidal Endothelium Is Associated with Decreased Expression of CD13. The Journal of Immunology
    Yazid J. Resheq et al.
    (See online at https://doi.org/10.4049/jimmunol.1600466)
  • Optimized human platelet lysate as novel basis for a serum-, xeno- and additive-free corneal endothelial cell and tissue culture. J Tissue Eng Regen Med
    Thieme D, Reuland L, Lindl T, Kruse F, Fuchsluger T
    (See online at https://doi.org/10.1002/term.2574)
  • Ménage-à-Trois: The Ratio of Bicarbonate to CO2 and the pH Regulate the Capacity of Neutrophils to Form NETs. Frontiers inImmunology
    Maueröder et al.
    (See online at https://doi.org/10.3389/fimmu.2016.00583)
 
 

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