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Characterization of the two receptor-kinases SOBIR1/EVR and BAK1 as co-receptors of the receptor-like protein RLP30 from Arabidopsis thaliana

Applicant Dr. Andrea A. Gust
Subject Area Organismic Interactions, Chemical Ecology and Microbiomes of Plant Systems
Term from 2014 to 2018
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 255705282
 
Plants have adapted defence mechanisms to resist microbial infection. Binding of microbial ligands to transmembrane receptors that are located at the cell surface trigger intracellular re-programming eventually leading to restriction of pathogen growth. We have associated one member of the Arabidopsis leucine-rich repeat (LRR) receptor-like proteins, RLP30, with a specific function as pattern recognition receptor for a novel elicitor activity from the fungal pathogen Sclerotinia sclerotiorum. Moreover, we have identified the two leucine-rich repeat receptor-like kinases BAK1 and SOBIR1/EVR as putative co-receptors of RLP30. The general objectives of this project will be to decipher the molecular mechanisms underlying RLP30-mediated pattern recognition and the subsequent signal transduction via the RLP30-BAK1-SOBIR1/EVR receptor machinery. Unravelling the mode of action of RLP30/BAK1/SOBIR1-mediated pattern perception will deepen our mechanistic understanding on SOBIR1/EVR as novel co-receptor for LRR-type receptor-like proteins and will broaden our knowledge on how plants adapt to a detrimental biotic environment.
DFG Programme Research Grants
 
 

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