Analysis of P5B ATPase Function

• Applicant: Privatdozent Dr. Eric Lambie
• Subject Area: Developmental Biology ; Cell Biology
• Term: from 2014 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 257149307

• Final Report Year: 2021

No abstract available

Publications

• Novel Alleles of gon-2, a C. elegans Ortholog of Mammalian TRPM6 and TRPM7, Obtained by Genetic Reversion Screens. PLoS One. 2015 Nov 25;10(11):e0143445
  Lambie, Eric J.; Bruce, Robert D.; Zielich, Jeffrey & Yuen, Sonia N.
  
• Establishment of a CRISPR/Cas9-based strategy for inducible protein dimerization. MicroPubl Biol. 2018 Apr 17. Erratum in: MicroPubl Biol. 2019 Dec 02
  Zielich J, Mangal S, Zanin E, Lambie E
  
• Overlapping expression patterns and functions of three paralogous P5B ATPases in Caenorhabditis elegans. PLoS One. 2018 Mar 16;13(3):e0194451
  Zielich, Jeffrey; Tzima, Elena; Schröder, Eva Ayla; Jemel, Faten; Conradt, Barbara & Lambie, Eric J.
  
• Rapamycin-induced proteindimerization as a tool for C. elegans research. MicroPubl Biol. 2018 Mar20. Erratum in: MicroPubl Biol. 2019 Dec 02
  Mangal S, Zielich J, Lambie E, Zanin E
  
• ATP13A2 deficiency disrupts lysosomal polyamine export. Nature. 2020 Feb;578(7795):419-424
  van Veen, Sarah; Martin, Shaun; Van den Haute, Chris; Benoy, Veronick; Lyons, Joseph; Vanhoutte, Roeland; Kahler, Jan Pascal; Decuypere, Jean-Paul; Gelders, Géraldine; Lambie, Eric; Zielich, Jeffrey; Swinnen, Johannes V.; Annaert, Wim; Agostinis, Patrizia; Ghesquière, Bart; Verhelst, Steven; Baekelandt, Veerle; Eggermont, Jan & Vangheluwe, Peter
  
• ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31198-31207
  Vrijsen, Stephanie; Besora-Casals, Laura; van Veen, Sarah; Zielich, Jeffrey; Van den Haute, Chris; Hamouda, Norin Nabil; Fischer, Christian; Ghesquière, Bart; Tournev, Ivailo; Agostinis, Patrizia; Baekelandt, Veerle; Eggermont, Jan; Lambie, Eric; Martin, Shaun & Vangheluwe, Peter