Konfokales Hochdurchsatz-Screening Laser-Raster Mikroskop

• Subject Area: Basic Research in Biology and Medicine
• Term: Funded in 2014
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 257897648

• Final Report Year: 2018

Final Report Abstract

No abstract available

Publications

• (2018) Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure. The Journal of clinical investigation 128 (11) 5056–5072
  Armacki, Milena; Trugenberger, Anna Katharina; Ellwanger, Ann K.; Eiseler, Tim; Schwerdt, Christiane; Bettac, Lucas; Langgartner, Dominik; Azoitei, Ninel; Halbgebauer, Rebecca; Groß, Rüdiger; Barth, Tabea; Lechel, André; Walter, Benjamin M.; Kraus, Johann
  
• A Dynamic Role of TBX3 in the Pluripotency Circuitry. Stem Cell Reports. 2015 Dec 8;5(6):1155-1170
  Russell R, Ilg M, Lin Q, Wu G, Lechel A, Bergmann W, Eiseler T, Linta L, Kumar P P, Klingenstein M, Adachi K, Hohwieler M, Sakk O, Raab S, Moon A, Zenke M, Seufferlein T, Schöler HR, Illing A, Liebau S, Kleger A
  
• Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion. J Biol Chem. 2016 Jan 1;291(1):462-77
  Eiseler T, Wille C, Koehler C, Illing A, Seufferlein T
  
• Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation. J Cell Sci. 2016 Jun 15;129(12):2416-29
  Sroka R, Van Lint J, Katz SF, Schneider MR, Kleger A, Paschke S, Seufferlein T, Eiseler T
  
• Tbx3 fosters pancreatic cancer growth by increased angiogenesis and activin/nodaldependent induction of stemness. Stem Cell Res. 2016 Sep;17(2):367-378
  Perkhofer L, Walter K, Costa IG, Carrasco MC, Eiseler T, Hafner S, Genze F, Zenke M, Bergmann W, Illing A, Hohwieler M, Köhntop R, Lin Q, Holzmann KH, Seufferlein T, Wagner M, Liebau S, Hermann PC, Kleger A, Müller M
  
• (2017). Generic wound signals initiate regeneration in missing-tissue contexts. Nat. Comm. 8: 2282
  Suthira Owlarn, Felix Klenner, David Schmidt, Franziska Rabert, Antonio Tomasso, Hanna Reuter, Medhanie A. Mulaw, Sören Moritz, Luca Gentile, Gilbert Weidinger, and Kerstin Bartscherer
  
• Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling. Gut. 2017 Mar;66(3):473-486
  Hohwieler M, Illing A, Hermann PC, Mayer T, Stockmann M, Perkhofer L, Eiseler T, Antony JS, Müller M, Renz S, Kuo CC, Lin Q, Sendler M, Breunig M, Kleiderman SM, Lechel A, Zenker M, Leichsenring M, Rosendahl J, Zenke M, Sainz B Jr, Mayerle J, Costa IG, Seufferlein T, Kormann M, Wagner M, Liebau S, Kleger A
  
• The armadillo protein p0071 controls KIF3 motor transport. J Cell Sci. 2017 Oct 1;130(19):3374-3387
  Becher A, Eiseler T, Porzner M, Walther P, Keil R, Bobrovich S, Hatzfeld M, Seufferlein T
  
• PKD regulates actin polymerization, neutrophil deformability, and transendothelial migration in response to fMLP and trauma. J Leukoc Biol. 2018 Sep;104(3):615-630
  Wille C, Eiseler T, Langenberger ST, Richter J, Mizuno K, Radermacher P, Knippschild U, Huber-Lang M, Seufferlein T, Paschke S