Chemical tools for the elucidation of the role of the acid sphingomyelinase under physiological or pathological conditions

• Applicant: Professor Dr. Christoph Arenz
• Subject Area: Biological and Biomimetic Chemistry ; Organic Molecular Chemistry - Synthesis and Characterisation
• Term: from 2014 to 2022
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 266895703

The aim of the project is to investigate the acid sphingomyelinase in physiological and pathological contexts. Besides the Niemann-Pick-Disease, the characterization of the pathophysiological role of this enzyme is within the main focus. An additional goal is the identification and characterization of novel mall molecule inhibitors of the acid sphingomyelinase.

• DFG Programme: Research Grants