Downstream signalling of hippocampal ensembles in the entorhinal cortex (A01)

• Subject Area: Molecular Biology and Physiology of Neurons and Glial Cells
• Term: from 2015 to 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 243553651

Cognitive or behavioral activity goes along with the activation of multiple local networks. We hypothesize that the corresponding ensembles form different representations, in line with the distributed information processing observed at the systems level. We will study progagating network activity in the hippocampus and the medial entorhinal cortex, a prominent model system for spatial memory formation. Using different biophysical, molecular and morphological methods we will identify the differences and commonalities of distinct ensembles in these areas.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1134: Functional ensembles: cellular components, patterned activity and plasticity of co-active neurons in local networks
• Applicant Institution: Ruprecht-Karls-Universität Heidelberg
• Project Head: Professor Dr. Andreas Draguhn