The role of glutamatergic inhibition in visual processing (C08)

• Subject Area: Molecular Biology and Physiology of Neurons and Glial Cells ; Cognitive, Systems and Behavioural Neurobiology
• Term: from 2015 to 2022
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 154113120

We recently found that GABAergic inhibition is required for direction-selective responses in the fruit fly visual system, highlighting interesting parallels to visual motion processing in the vertebrate retina. We hypothesize that glutamatergic inhibition is also required, and mediates the ON and OFF pathway split. Using a combination of pharmacology and genetic tools, we will study the role of glutamatergic inhibition in the fly visual system, as well as the interactions between ON and OFF pathway.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 889: Cellular Mechanisms of Sensory Processing
• Applicant Institution: Georg-August-Universität Göttingen
• Project Head: Professorin Dr. Marion Silies