GRK 370:  Biochemistry of Nucloeprotein Complexes

• Subject Area: Basic Research in Biology and Medicine
• Term: from 1997 to 2006
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 272085

The subject of this research training group is the analysis of the interactions between proteins and nucleic acids. The research programme deals with the processes of virus replication, regulation of transcription, translation, RNA processing and RNA stability as well as the mechanisms of DNA cleavage and modification by enzymes. The graduate programme is supported by research groups representing a broad spectrum and includes groups that are just at the beginning of a mechanistic explanation of a biological or medicinical phenomenon as well as groups that study the interaction between proteins and nucleic acids at atomic resolution. The aim of the study programme is to familiarize the graduate students with many methods, from genetic analysis to detailed enzymological techniques. This is achieved by short periods of practical training, where the graduate students have the possibility to learn methods that the research groups are especially acquainted with. This laboratory work gives the graduate students the chance to gain insight into the projects of their colleagues. There is a particular emphasis on intense discussions within the seminars held by students and professors. Students are encouraged to cooperate with their fellow students. Another focus of attention is given to workshops where the graduate students have the opportunity to discuss their projects with external experts.

• DFG Programme: Research Training Groups
• Applicant Institution: Justus-Liebig-Universität Gießen
• Spokesperson: Professor Dr. Alfred Pingoud (†)
• Participating Researchers: Professor Dr. Aria Baniahmad; Professor Dr. Albrecht Bindereif; Professor Dr. Trinad Chakraborty; Professor Dr. Eugen Domann; Professorin Dr. Elena Evguenieva-Hackenberg; Professor Dr. Karl Forchhammer; Professor Dr. Wolfram H. Gerlich; Professor Dr. Albert Jeltsch; Professor Dr. Michael Kann; Professorin Dr. Gabriele Klug; Professor Dr. Michael Niepmann; Professor Dr. Stephan Pleschka; Professor Dr. Rainer Renkawitz; Professor Dr. Tillmann Hans Rümenapf; Professor Dr. Heinz-Jürgen Thiel; Dr. Anke Treuner-Lange; Dr. Wolfgang Wende