GRK 760:  Medicinal Chemistry: Molecular Recognition - Ligand-Receptor Interactions

• Subject Area: Medicine ; Basic Research in Biology and Medicine
• Term: from 2002 to 2011
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 273397

Medicinal Chemistry is a chemistry-based discipline also involving aspects of biological, medical and pharmaceutical sciences. It is concerned with the discovery, design, identification and preparation of biologically active compounds and the interpretation of their mode of action at the molecular level and the study of their metabolites. The research training group supports highly qualified students from Germany and abroad who have graduated, particularly, from Chemistry, Pharmacy, Biochemistry or Biology (language of the study and research programme is English). It is the objective of the research training group that the graduates, beyond acquiring special project-related knowledge and skills, obtain broad education in all essential aspects of Medicinal Chemistry in order to prepare them for future scientific work in academic or industrial drug research. Advances in drug therapy are increasingly achieved by using structure- and target-based approaches of drug design. Consequently, there is growing significance of basic research combining methods of Chemistry, Biophysics, Molecular Biology, Molecular Pharmacology and computer-aided drug design to identify the mechanisms of action and interaction on a molecular level. The program reflects the strongly interdisciplinary character of biomedical drug research, as projects with emphasis on Organic Chemistry, Biophysics, Bioanalytics, Molecular and Cellular Biology, Pharmacology or Biochemistry are included in the research programme. The topics comprise special receptors and their ligands as well as artificial (model) receptor systems and the development of methods for the investigation of ligand receptor interactions.

• DFG Programme: Research Training Groups
• Applicant Institution: Universität Regensburg
• Spokesperson: Professor Dr. Armin Buschauer (†)
• Participating Researchers: Dr. Günther Bernhardt; Professor Dr. Stefan Dove; Professor Dr. Sigurd Elz; Professor Dr. Achim Goepferich; Professorin Dr. Ruth M. Gschwind; Professor Dr. Hans Robert Kalbitzer; Professor Dr. Burkhard König; Professorin Dr. Daniela N. Männel; Professor Dr. Oliver Reiser; Professor Dr. Jens Schlossmann; Professor Dr. Roland Seifert