The cortical signature of nociception and pain in circuits of the lateral somatosensory system (B05)

• Subject Area: Epidemiology and Medical Biometry/Statistics
• Term: from 2015 to 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 255156212

This project targets oscillatory evoked and ongoing (spontaneous) responses as a correlate of nociceptive information and pain perception in the brain of rodents and humans. In rodents, multi-units and local field potentials from cortical and thalamic sites will be acquired during phasic, tonic and chronic pain. In humans, specific locations of evoked and ongoing nociceptive activity will be identified using neuroimaging and parallel electro-magnetoencephalographic (EEG-MEG) recordings with aubsequent source analyses and time frequency analyses. In this translational approach cross frequency- and cross regional coupling of oscillatory activity will used to identify a neural signature of nociception and pain.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1158: From nociception to chronic pain: Structure-function properties of neural pathways and their reorganisation
• Applicant Institution: Ruprecht-Karls-Universität Heidelberg
• Project Heads: Professor Dr. Ulf Baumgärtner; Professor Dr. Andreas Draguhn; Privatdozent Dr. André Rupp