Reversible Single-Chain Folding of Macromolecules via Non-Covalent Interactions (A01)

• Subject Area: Preparatory and Physical Chemistry of Polymers
• Term: from 2016 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 259079535

In contrast to the at least partially understood folding of polypeptides to proteins, the understanding of the mechanistic principles of the folding of polymers into single chain nanoparticles (SCNPs) is still in its infancy. Complex macromolecules with several novel covalent and non-covalent (photochemically controlled) folding points will be explored and their compaction studied in detail on an atomistic level using a variety of sophisticated NMR-spectroscopic methods.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1176: Molekulare Strukturierung weicher Materie
• Major Instrumentation: Isothermale Titrationskalorimetrie
• Instrumentation Group: 8650 Spezielle Kalorimeter
• Applicant Institution: Karlsruher Institut für Technologie
• Project Heads: Professor Dr. Christopher Barner-Kowollik; Professor Dr. Burkhard Luy