Applikation wachstumsfaktorspezifischer Gene (BMP-2) mittel Copolymer Protected Gene Vector (COPROG) zur Beschleunigung der Implantateinheilung in vivo

Applicants Professor Dr. Gerhard Schmidmaier; Professor Dr. Axel Stemberger

Subject Area Orthopaedics, Traumatology, Reconstructive Surgery

Term from 2006 to 2009

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 28834694

Final Report Year 2009

Final Report Abstract

No abstract available

"A fibrin glue composition as carrier for nucleic acid vectors," Pharm. Res. 25(12), 2946 (2008)
Ulrike Schillinger, Gabriele Wexel, Christian Hacker, Martin Kullmer, Christian Koch, Michael Gerg, Stephan Vogt, Peter Ueblacker, Thomas Tischer, Daniel Hensler, Jonas Wilisch, Joachim Aigner, Axel Walch, Axel Stemberger, Christian Plank
8th World Biomaterials Congress, 28.05.-01-06.2008, Amsterdam, Niederlande: "Application of BMP-2 specific plasmids in fibrin glue does not promote implant fixation"
Faensen, B; Wildemann, B; Hain, C; Höhne, J; Funk, Y; Planck, C; Stemberger, A.; Schmidmaier, G
Deutscher Kongreß für Orthopädie und Unfallchirurgie 22.-25.10.2008, Berlin. "Lokal applizierte, BMP-2 spezifische Plasmide in Fibrinkleber verbessern nicht die Implantateinheilung"
Faensen B., Wildemann B., Schmidmaier G.
55th Meeting oft he Orthopedic Research Society 22,-25,02,2009, Las Vegas, USA: "Impaired Implant fixation under the Influence of locally applied BMP-2 specific Plasmids"
Faensen B., Wildemann B., Schmidmaier G., Hain C, Höhne J., Funke Y., Planck C., Stemberger A.