Modulation of neural mechanisms underlying crossmodal predictions (B01)

• Subject Area: Biological Psychology and Cognitive Neuroscience ; Cognitive, Systems and Behavioural Neurobiology ; Molecular Biology and Physiology of Neurons and Glial Cells
• Term: since 2016
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 261402652

Using MEG and EEG, we will investigate the dynamics of neural oscillations involved in uni- and crossmodal temporal predictions. Recordings in healthy participants will be combined with studies in patients with Parkinson’s disease (PD) who have impairments in updating stimulus predictions and in judging event timing. We will modulate the neural mechanisms underlying temporal predictions by manipulation of relevant sensory cues and by neurostimulation approaches. These will include transcranial alternating current stimulation (tACS) in healthy participants and deep brain stimulation (DBS) in the patients. Furthermore, we will implement ensemble oscillator models to account for the observed modulation of uni- and crossmodal predictions.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 169: Crossmodal Learning: Adaptivity, Prediction and Interaction
• International Connection: China
• Applicant Institution: Universität Hamburg
• Project Heads: Professor Dr. Andreas K. Engel; Professor Dr. Xiaolin Hu, until 12/2019; Professor Dr. Dan Zhang