Tropomyosin 1 and End-binding protein 1 in mRNA transport

• Applicants: Anne Ephrussi, Ph.D.; Professor Dr. Janosch Hennig
• Subject Area: General Genetics and Functional Genome Biology ; Biochemistry ; Developmental Biology ; Structural Biology ; Cell Biology
• Term: from 2016 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 313646688

• Final Report Year: 2024

No abstract available

Publications

• Molecular basis of mRNA transport by a kinesin-1–atypical tropomyosin complex. Genes & Development, 35(13-14), 976-991.
  Dimitrova-Paternoga, Lyudmila; Jagtap, Pravin Kumar Ankush; Cyrklaff, Anna; Vaishali, NA; Lapouge, Karine; Sehr, Peter; Perez, Kathryn; Heber, Simone; Löw, Christian; Hennig, Janosch & Ephrussi, Anne
  
• Validation and classification of RNA binding proteins identified by mRNA interactome capture. RNA, 27(10), 1173-1185.
  Vaishali, NA; Dimitrova-Paternoga, Lyudmila; Haubrich, Kevin; Sun, Mai; Ephrussi, Anne & Hennig, Janosch
  
• Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport. Nature Structural & Molecular Biology, 31(3), 476-488.
  Heber, Simone; McClintock, Mark A.; Simon, Bernd; Mehtab, Eve; Lapouge, Karine; Hennig, Janosch; Bullock, Simon L. & Ephrussi, Anne