The role of TRPC6 channels in neutrophil recruitment

Applicant Professor Dr. Albrecht Schwab

Subject Area Anatomy and Physiology

Term from 2016 to 2020

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 313658831

Final Report Year 2021

Final Report Abstract

No abstract available

2018. The function of TRP channels in neutrophil granulocytes. Pflügers Arch 470:1017–1033
Najder K, Musset B, Lindemann O, Bulk E, Schwab A, Fels B
(See online at https://doi.org/10.1007/s00424-018-2146-8)
2020. Intravascular adhesion and recruitment of neutrophils in response to CXCL1 depends on their TRPC6 channels. J Mol Med 98: 349-360
Lindemann O, Rossaint J, Najder K, Schimmelpfennig S, Hofschröer V, Wälte M, Fels B, Oberleithner H, Zarbock A, Schwab A
(See online at https://doi.org/10.1007/s00109-020-01872-4)
2020. pH-channeling in cancer: How pH-dependence of cation channels shapes cancer pathophysiology. Cancers (Basel) 12: E2484
Pethő Z, Najder K, Carvalho T, McMorrow R, Todesca LM, Rugi M, Bulk E, Chan A, Löwik CWGM, Reshkin SJ, Schwab A
(See online at https://doi.org/10.3390%2Fcancers12092484)
2020. Role of the Intracellular Sodium Homeostasis in Chemotaxis of Activated Murine Neutrophils. Front Immunol 11: 2124
Najder K, Rugi M, Lebel M, Schröder J, Oster L, Schimmelpfennig S, Sargin S, Pethö ZD, Bulk E, Schwab A
(See online at https://doi.org/10.3389%2Ffimmu.2020.02124)
2021. Ion channels orchestrate pancreatic ductal adenocarcinoma progression and therapy. Front Pharmacol
Hofschröer V, Najder K, Rugi M, Bouazzi R, Cozzolino M, Arcangeli A, Panyi G, Schwab A
(See online at https://doi.org/10.3389/fphar.2020.586599)