Repertoire and antigen recognition of brain-infiltrating immune cells in progressive MS

Applicant Privatdozent Dr. Klaus Dornmair

Subject Area Molecular and Cellular Neurology and Neuropathology

Term from 2017 to 2020

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 340260765

Final Report Year 2021

Final Report Abstract

No abstract available

(2019) Communication of CD8+ T cells with mononuclear phagocytes in multiple sclerosis brain lesions. Ann. Clin. Transl. Neurol. 6:1151-1164
Konjevic-Sabolek, M., Held, K., Beltrán, E., Niedl, A.G., Meinl, E., Hohlfeld, R., Lassmann, H., and Dornmair, K.
(See online at https://doi.org/10.1002/acn3.783)
(2019) Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis. J. Clin. Invest. 129:4758-4768
Beltrán, E., Gerdes, L.A., Hansen, J., Flierl-Hecht, A., Krebs, S., Blum, H., Ertl-Wagner, B., Barkhof, F., Kümpfel, T., Hohlfeld, R., and Dornmair, K.
(See online at https://doi.org/10.1172/jci128475)
(2021) Archeological neuroimmunology: Resurrection of a pathogenic immune response from a historical case sheds light on human autoimmune encephalomyelitis and multiple sclerosis. Acta Neuropathol. 141(1):67-83
Beltrán, E., Paunovic, M., Gebert, D., Cesur, E., Jeitler, M., Höftberger, R., Malotka, J., Mader, S., Kawakami, N., Meinl, E., Bradl, M., Dornmair, K., and Lassmann, H.
(See online at https://doi.org/10.1007/s00401-020-02239-2)