Project Details
Projekt
Electrical stimulation of articular cartilage: Evaluation of its potential for the repair of osteochondral defects in situ (C02)
Subject Area
Orthopaedics, Traumatology, Reconstructive Surgery
Biomaterials
Biomaterials
Term
since 2017
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 299150580
One project goal is to develop a stimulation device for targeted electrical stimulation of articular cartilage for future human application. To this end, a demonstrator of a multi-electrode array implant is developed, including a feedback system for determining the electrical conductivity and dielectric properties of the surrounding tissue, using a human ex vivo model of the knee joint. Furthermore, the rheological, tribological, and biological properties of biphasic scaffold structures to repair osteochondral defects are investigated. Therefore, further studies on gender-specific molecular patterns of chondrogenic and osteogenic cell differentiation are conducted.
DFG Programme
Collaborative Research Centres
Subproject of
SFB 1270:
ELectrically Active ImplaNts - ELAINE
Applicant Institution
Universität Rostock
Project Heads
Professor Dr. Rainer Bader; Privatdozentin Dr. Anika Jonitz-Heincke, since 7/2021; Professor Dr.-Ing. Hermann Seitz
