Exploring the efficacy of novel photobactericidals against planktonic and biofilm growing uropathogenic bacteria

• Applicant: Professorin Dr. Anzhela Galstyan
• Subject Area: Biological and Biomimetic Chemistry ; Reproductive Medicine, Urology
• Term: from 2018 to 2022
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 388056781

• Final Report Year: 2023

No abstract available

Publications

• Breaching the wall: morphological control of efficacy of phthalocyanine based photoantimicrobials., J. Mater. Chem. B, (2018), 6, 4630 – 4637
  Galstyan, Anzhela & Dobrindt, Ulrich
  
• Determining and unraveling origins of reduced photoinactivation efficacy of bacteria in milk. J. Photochem. Photobiol. B Biol. (2019), 197, 111554
  Galstyan, Anzhela & Dobrindt, Ulrich
  
• Exploring the Impact of Coordination-Driven Self Assembly on the Antibacterial Activity of Low-Symmetry Phthalocyanines. ACS Appl. Bio Mater. (2020), 3, 400–411
  Galstyan, Anzhela; Ricker, Andrea; Nüsse, Harald; Klingauf, Jürgen & Dobrindt, Ulrich
  
• Chitosan‐Silicon Phthalocyanine Conjugate as Effective Photo‐ Functional Hydrogel for Tracking and Killing of Bacteria, Eur. J. Org. Chem. (2020), 47, 7327-7332
  Strokov, Konstantin & Galstyan, Anzhela
  
• Dye extract of calyces of Hibiscus sabdariffa has photodynamic antibacterial activity: a prospect for sunlight driven fresh produce sanitation. Food Science and Nutrition. (2020), 8, 3200 – 3211
  Majiya, Hussaini & Galstyan, Anzhela
  
• Facile fabrication of silicon(IV)phthalocyanine embedded poly(vinyl alcohol)-based antibacterial and antifouling interfaces, ACS Appl. Bio Mater. (2020), 3(6), 3751–3760
  Strokov, Konstantin; Schäfer, Andreas H.; Dobrindt, Ulrich & Galstyan, Anzhela
  
• Turning photons into drugs: phthalocyanine-based photosensitizers as efficient photoantimicrobials, Chem. Eur. J., (2021), 27(6): 1903–1920 (invited review article)
  Galstyan, Anzhela
  
• π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation. Chem. – A Eur. J., (2020), 26, 8262-8266
  Galstyan, Anzhela; Maurya, Yogesh Kumar; Zhylitskaya, Halina; Bae, Youn Jue; Wu, Yi‐Lin; Wasielewski, Michael R.; Lis, Tadeusz; Dobrindt, Ulrich & Stępień, Marcin
  
• Biodegradable supramolecular micelles via host-guest interaction of cyclodextrin-terminated polypeptides and adamantane-terminated polycaprolactones. Chem. Commun. (2021), 57(74), 9446-9449
  Pottanam Chali, Sharafudheen; Azhdari, Suna; Galstyan, Anzhela; Gröschel, André H. & Ravoo, Bart Jan
  
• Umbelliferone Decorated Water-soluble Zinc(II) Phthalocyanines - In Vitro Phototoxic Antimicrobial Anti-cancer Agents. Chem. Eur. J. (2021), 27(59), 14672-14680
  Sowa, Andrea; Höing, Alexander; Dobrindt, Ulrich; Knauer, Shirley K.; Galstyan, Anzhela & Voskuhl, Jens
  
• Influence of photosensitizer concentration and polymer composition on photoinduced antimicrobial activity of PVA and PVA‑chitosan‑based electrospun nanomaterials cross‑linked with tailor‑made silicon(IV) phthalocyanine, Photochem. & Photobiol. Sciences., (2022), 21,1387–1398
  Galstyan, Anzhela & Strokov, Konstantin
  
• Regulation of photo triggered cytotoxicity in electrospun nanomaterials: role of photosensitizer binding mode and polymer identity, Nanoscale Adv. (2022) 4 (1), 200-210
  Galstyan, Anzhela; Majiya, Hussaini & Dobrindt, Urlich