Structural and functional characterization of a SKI sub complex in Saccharomyces cerevisiae

• Applicant: Professor Dr. Roland Beckmann
• Subject Area: Structural Biology ; Biochemistry
• Term: from 2017 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 390891884

• Final Report Year: 2022

No abstract available

Publications

• A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes. The EMBO Journal, 38(14).
  Zhang, Elodie; Khanna, Varun; Dacheux, Estelle; Namane, Abdelkader; Doyen, Antonia; Gomard, Maïté; Turcotte, Bernard; Jacquier, Alain & Fromont‐Racine, Micheline
  
• Structure of the 80S ribosome–Xrn1 nuclease complex. Nature Structural & Molecular Biology, 26(4), 275-280.
  Tesina, Petr; Heckel, Elisabeth; Cheng, Jingdong; Fromont-Racine, Micheline; Buschauer, Robert; Kater, Lukas; Beatrix, Birgitta; Berninghausen, Otto; Jacquier, Alain; Becker, Thomas & Beckmann, Roland
  
• A structural inventory of native ribosomal ABCE1‐43S pre‐initiation complexes. The EMBO Journal, 40(1).
  Kratzat, Hanna; Mackens‐Kiani, Timur; Ameismeier, Michael; Potocnjak, Mia; Cheng, Jingdong; Dacheux, Estelle; Namane, Abdelkader; Berninghausen, Otto; Herzog, Franz; Fromont‐Racine, Micheline; Becker, Thomas & Beckmann, Roland
  
• Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369(6508), 1249-1255.
  Thoms, Matthias; Buschauer, Robert; Ameismeier, Michael; Koepke, Lennart; Denk, Timo; Hirschenberger, Maximilian; Kratzat, Hanna; Hayn, Manuel; Mackens-Kiani, Timur; Cheng, Jingdong; Straub, Jan H.; Stürzel, Christina M.; Fröhlich, Thomas; Berninghausen, Otto; Becker, Thomas; Kirchhoff, Frank; Sparrer, Konstantin M. J. & Beckmann, Roland
  
• Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. PLOS Biology, 18(7), e3000780.
  Wells, Jennifer N.; Buschauer, Robert; Mackens-Kiani, Timur; Best, Katharina; Kratzat, Hanna; Berninghausen, Otto; Becker, Thomas; Gilbert, Wendy; Cheng, Jingdong & Beckmann, Roland