Project Details
Projekt
Topology, regulation and function of acid sphingomyelinase in death receptor signaling
Applicant
Professor Dr. Stefan Schütze
Subject Area
Anatomy and Physiology
Term
from 2007 to 2014
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 39297910
Final Report Year
2009
Final Report Abstract
No abstract available
Publications
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(2008) Reduced acid sphingomyelinase activity improves lung edema and gas exchanges in a newborn piglet lavage model. Am. J. of Resp. and Crit. Care Med. 177, 1233-1241
von Bismarck, P., Wistädt, C.-F.G., Klemm, K., Winoto-Morbach, S., Uhlig, U., Adam, D. Schütze, S., Uhlig, S., Lachmann, B., and Krause, M.F.
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(2008). Evidence for an association of prion protein and sphingolipid-mediated signaling. J. Neurochem. 106, 1459-1470
Schmalzbauer, R., Eigenbrod, S., Winoto-Morbach, S., Xiang, W., Schütze, S., Bertsch, U., Kretschmar, H.A.
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Regulation of TNF-R1 and CD95 signalling by receptor compartmentalization. Nat. Rev. Mol. Cell Biol. 9, 655-662 (2008)
Schütze, S., Tchikov, V., and Schneider-Brachert, W.
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(2009) Impact of TNF-R1 and CD95 internalization on apoptotic and antiapoptotic signaling. Results Probl. Cell Differ. 2009 Jan 9. [Epub ahead of print]
Schütze, S. and Schneider-Brachert, W.
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(2009) Intracellular IL-15 controls mast cell survival. Exp. Cell Res.315, 3064-3075
Mirghomizadeh-F., Winoto-Morbach, S., Orinska, Z., Lee, K.-H., Schütze, S., Bulfone-Paus, S.
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(2009) Riboflavin kinase couples TNF Receptor 1 to NADPH oxidase. Nature 460, 1159-1163
Yazdanpanah, B., Wiegmann, K., Tchikov, V., Krut, O., Pongratz, C., Schramm, M., Kleinridders, A., Wunderlich, T., Kashkar, H., Utermöhlen, O., Brüning, J.C., Schütze, S., Krönke, M.
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(2009) Selective NF-kappaB inhibition, but not dexamethasone, decreases acute lung injury in a newborn piglet airway inflammation model. Pulm. Pharmacol. Therap. 2009 Feb. 28 [Epub ahead of print]
Von Bismarck, P., Klemm, K., Wistädt, C.F.G., Winoto-Morbach, S., Schütze, S., Krause, M.F.
