Observer and control design for mass structured cell populations

• Applicant: Professor Dr. Alexander Schaum
• Subject Area: Automation, Mechatronics, Control Systems, Intelligent Technical Systems, Robotics
• Term: since 2018
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 395461267

In this project the results of the preceding project DFG 395461267 observer and tracking control design for cell population models shall be deepened and extended. While in the preceding project the focus was on the analysis of cell population balance models on the basis of approximations of the partial integro-differential equations by finite differences (FD) and the studies were mainly constrained to the anaerobic yeast fermentation, in the applied continuation project the following points are focused on: (i) aerobic as well as anaerobic process conditions for the yeast fermentation, (ii) inclusion of additional sensors, (iii) alternative numerical approximation methods, in particular the cell average method (CAM) and the quadrature method of moments (QMM), (iv) explicit methods for model order reduction (MOR), as well as (v) the transferability to other cultures like, e.g., microalgae. A particular focus shall be on the robustness analysis of the obtained observability and controllability properties, as well as the designed observers and feedback controllers.

• DFG Programme: Research Grants
• International Connection: Italy
• Cooperation Partner: Professorin Dr. Stefania Tronci