Investigation of the mechanisms of blue light-induced biological effects on skin and skin cells

• Applicant: Privatdozent Dr. Christian Opländer
• Subject Area: Medical Physics, Biomedical Technology
• Term: from 2018 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 403583563

• Final Report Year: 2024

No abstract available

Publications

• The impact of non-toxic blue light (453 nm) on cellular antioxidative capacity, TGF-β1 signaling, and myofibrogenesis of human skin fibroblasts. Journal of Photochemistry and Photobiology B: Biology, 209, 111952.
  Krassovka, Julia M.; Suschek, Christoph V.; Prost, Max; Grotheer, Vera; Schiefer, Jennifer L.; Demir, Erhan; Fuchs, Paul C.; Windolf, Joachim; Stürmer, Ewa K. & Opländer, Christian
  
• Characterization of Blue Light Treatment for Infected Wounds: Antibacterial Efficacy of 420, 455, and 480 nm Light-Emitting Diode Arrays Against Common Skin Pathogens Versus Blue Light-Induced Skin Cell Toxicity. Photobiomodulation, Photomedicine, and Laser Surgery, 39(5), 339-348.
  Plattfaut, Isabell; Demir, Erhan; Fuchs, Paul C.; Schiefer, Jennifer L.; Stürmer, Ewa K.; Brüning, Anne K.E. & Opländer, Christian
  
• Plasma medicine and wound management: Evaluation of the antibacterial efficacy of a medically certified cold atmospheric argon plasma jet. International Journal of Antimicrobial Agents, 57(5), 106319.
  Plattfaut, Isabell; Besser, Manuela; Severing, Anna-Lena; Stürmer, Ewa K. & Opländer, Christian
  
• Enhancement of Nitric Oxide Bioavailability by Modulation of Cutaneous Nitric Oxide Stores. Biomedicines, 10(9), 2124.
  Suschek, Christoph V.; Feibel, Dennis; von Kohout, Maria & Opländer, Christian
  
• Phototherapy of Pseudomonas aeruginosa -Infected Wounds: Preclinical Evaluation of Antimicrobial Blue Light (450–460 nm) Using In Vitro Assays and a Human Wound Skin Model. Photobiomodulation, Photomedicine, and Laser Surgery, 40(12), 800-809.
  Leder, Marie-Charlotte D.; Bagheri, Mahsa; Plattfaut, Isabell; Fuchs, Paul C.; Brüning, Anne K.E.; Schiefer, Jennifer L. & Opländer, Christian
  
• Can Cold Atmospheric Plasma Be Used for Infection Control in Burns? A Preclinical Evaluation. Biomedicines, 11(5), 1239.
  Bagheri, Mahsa; von Kohout, Maria; Zoric, Andreas; Fuchs, Paul C.; Schiefer, Jennifer L. & Opländer, Christian
  
• Gas Flow-Dependent Modification of Plasma Chemistry in μAPP Jet-Generated Cold Atmospheric Plasma and Its Impact on Human Skin Fibroblasts. Biomedicines, 11(5), 1242.
  Feibel, Dennis; Golda, Judith; Held, Julian; Awakowicz, Peter; Schulz-von, der Gathen Volker; Suschek, Christoph V.; Opländer, Christian & Jansen, Florian
  
• Low-Dose Blue Light (420 nm) Reduces Metabolic Activity and Inhibits Proliferation of Human Dermal Fibroblasts. Life, 13(2), 331.
  Brüning, Anne K. E.; Schiefer, Jennifer L.; Fuchs, Paul C.; Petzsch, Patrick; Köhrer, Karl; Suschek, Christoph V.; Stürmer, Ewa K. & Opländer, Christian
  
• High-Intensity Blue Light (450–460 nm) Phototherapy for Pseudomonas aeruginosa -Infected Wounds. Photobiomodulation, Photomedicine, and Laser Surgery, 42(5), 356-365.
  Zoric, Andreas; Bagheri, Mahsa; von Kohout, Maria; Fardoust, Tara; Fuchs, Paul C.; Schiefer, Jennifer L. & Opländer, Christian
  
• The Antimicrobial Efficacy of Topically Applied Mafenide Acetate, Citric Acid and Wound Irrigation Solutions Lavanox and Prontosan against Pseudomonas aeruginosa. Antibiotics, 13(1), 42.
  Bagheri, Mahsa; Zoric, Andreas; von Kohout, Maria; Fuchs, Paul; Schiefer, Jennifer & Opländer, Christian