Project Details
Projekt
Purinergic receptors in adipose tissue inflammation and adaptive thermogenesis (A10)
Subject Area
Cell Biology
Term
since 2018
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 335447717
Obesity is characterized by disturbed energy metabolism in white and brown adipose tissue. These metabolic abnormalities trigger inflammatory responses, thereby strongly contributing to the development of chronic inflammatory metabolic diseases such as type 2 diabetes. In this project, we aim to investigate the functional relevance of extracellular adenine nucleotides and purinergic receptors for lipid processing, for adipogenic differentiation and for inflammatory responses in white and brown adipose tissue.
DFG Programme
Collaborative Research Centres
Applicant Institution
Universität Hamburg
Project Heads
Professor Dr. Jörg Heeren; Professor Dr. Friedrich Koch-Nolte, until 6/2022
