MPS-mouse: Mobile hand-held Magnetic Particle Spectroscopy

• Antragsteller: Dr. Patrick Vogel
• Fachliche Zuordnung: Medizinische Physik, Biomedizinische Technik
• Förderung: Förderung von 2018 bis 2021
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 412842756

• Erstellungsjahr: 2022

Zusammenfassung der Projektergebnisse

In this project, the feasibility of building a fully equipped, mobile, handheld Magnetic Particle Spectrometer (MPS) was investigated. The goal was to provide a cost-efficient and easy-to-use device to researcher in different fields. For that, cost-efficient (e.g., high performance microcontroller PSoC 5LP), easy-available or easy-to-build components (utilizing 3D-printing) have been developed and used to construct the MPS-MOUSE (MPS-MObile Universal Surface Explorer). In initial tests, the sensitivity of the receive chain, the performance of the transmit chain and the robustness of the hardware was sufficient for performing proof-of-concept experiments in different areas. E.g., material fingerprinting and characterization: besides the distinguishing of multiple SPION types (superparamagnetic iron oxide nanoparticles), non-magnetic materials, such as copper or aluminum, can be characterized. In addition, using the home-built camera-based tracking feature, the MPS-MOUSE can be tracked along large areas to visualize 2D surfaces.

Projektbezogene Publikationen (Auswahl)

• MPS-Maus – Mobiles Magnetspektrometer – DGMP #49 (Nürnberg), V149, 2018. – talk
  P. Vogel, M.A. Rückert, V.C. Behr
  
• MPS-mouse: first mobile Magnetic Particle Spectrometer – BMT #52 (Aachen), C3.6, 2018. – talk
  P. Vogel, M.A. Rückert, V.C. Behr
  
• First MPS Mobile Universal Surface Explorer – IWMPI #9 (New York), ID172, 2019 – poster
  P. Vogel, M.A. Rückert, V.C. Behr
  
• Magnetic Particle Spectroscopy – MObile Universal Surface Explorer – ICMRM #15 (Paris), P51, 2019. – poster
  P. Vogel, M.A. Rückert, T. Kampf, V.C. Behr
  
• MPS MOUSE for SPION Specification and Standardization – ISMAP #3 (Ilmenau), 2019. – poster
  P. Vogel, M.A. Rückert, H. Brand, T. Kampf, V.C. Behr
  
• MPS-MOUSE – Mobiles Messinstrument für die Detektion erkrankter Wächterlymphknoten – DGMP #50 (Stuttgart), P30, 2019. – poster
  P. Vogel, S. Herz, M.A. Rückert, T. Kampf, T.A. Bley, V.C. Behr
  
• Superspeed Bolus Visualization for Vascular Magnetic Particle Imaging. IEEE Transactions on Medical Imaging, 39(6), 2133-2139.
  Vogel, Patrick; Ruckert, Martin A.; Kampf, Thomas; Herz, Stefan; Stang, Anton; Wockel, Lucas; Bley, Thorsten A.; Dutz, Silvio & Behr, Volker C.
  
• MPS-MObile Universal Surface Explorer for scanning large samples – IWMPI #10 (Würzburg), 2020/21. – poster
  C. Beck, M.A. Rückert, T. Kampf, V.C. Behr, and P. Vogel