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Non-invasive Monitoring of hemodynamic status in preterm infants: a prospective comparison of 3 different approaches including feasibility, reproducibility and association to relevant clinical short term outcome

Subject Area Pediatric and Adolescent Medicine
Term from 2018 to 2021
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 420536451
 
Final Report Year 2022

Final Report Abstract

Despite unforeseeable challenges due to COVID-19 and a national IT disruption due to a ransomware attack during his research fellowship from the DFG, Dr Schwarz designed and conducted a prospective clinical study and a simulation study evaluating multimodal noninvasive objective hemodynamic monitoring and especially non-invasive cardiac output monitoring (NiCO) of very preterm infants. The results show technical and practical issues regarding feasibility, reproducibility and the clinical relevance of Electrical Cardiometry in very preterm during the transitional period. At the time of this report final further analysis is almost complete. Moreover, Dr Schwarz conducted two literature reviews regarding NiCO and cardiovascular management in neonates.

Publications

  • Management of Neonatal Hypotension and Shock. Semin Fetal Neonatal Med. 2020 May 21:101121
    Schwarz CE, Dempsey EM
    (See online at https://doi.org/10.1016/j.siny.2020.101121)
  • Non-Invasive Cardiac Output Monitoring in Neonates Front. Pediatr. 2020
    O'Neill R, Dempsey EM, Garvey AA, Schwarz CE
    (See online at https://doi.org/10.3389/fped.2020.614585)
  • In-Silico Evaluation of Anthropomorphic Measurement Variations on Electrical Cardiometry in Neonates. Children (Basel). 2021 Oct 18;8(10):936
    Healy DB, Dempsey EM, O'Toole JM, Schwarz CE
    (See online at https://doi.org/10.3390/children8100936)
  • Signal Quality of Electrical Cardiometry and Perfusion Index in Very Preterm Infants. Neonatology. 2021 Sep 22:1-6
    Schwarz CE, O'Toole JM, Livingstone V, Pavel AM, Dempsey EM
    (See online at https://doi.org/10.1159/000518061)
 
 

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