[18F]FE-PE2I PET: a novel biomarker for Parkinson’s disease

• Applicant: Dr. Joachim Brumberg
• Subject Area: Nuclear Medicine, Radiotherapy, Radiobiology ; Clinical Neurology; Neurosurgery and Neuroradiology
• Term: from 2019 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 422567340

• Final Report Year: 2021

Final Report Abstract

No abstract available

Publications

• Dermal and cardiac autonomic fiber involvement in Parkinson's disease and multiple system atrophy. Neurobiol Dis. 2021
  Brumberg J, Kuzkina A, Lapa C, Mammadova S, Buck A, Volkmann J, Sommer C, Isaias IU, Doppler K.
  (See online at https://doi.org/10.1016/j.nbd.2021.105332)
• Brain metabolic alterations herald falls in patients with Parkinson's disease. Ann Clin Transl Neurol. 2020
  Isaias IU, Brumberg J, Pozzi NG, Palmisano C, Canessa A, Marotta G, Volkmann J, Pezzoli G
  (See online at https://doi.org/10.1002/acn3.51013)
• Detection Rate of 68Ga-PSMA Ligand PET/CT in Patients with Recurrent Prostate Cancer and Androgen Deprivation Therapy. Biomedicines. 2020; 8:511
  Brumberg J, Beckl M, Dierks A, Schirbel A, Krebs M, Buck A, Kübler H, Lapa C, Seitz AK
  (See online at https://doi.org/10.3390/biomedicines8110511)
• Differential diagnosis of parkinsonism: a head-to-head comparison of FDG PET and MIBG scintigraphy. npj Parkinson's Disease. 2020; 6:1
  Brumberg J, Schröter N, Blazhenets G, Frings L, Volkmann J, Lapa C, Jost WH, Isaias IU, Meyer PT
  (See online at https://doi.org/10.1038/s41531-020-00141-y)
• Simplified quantification of [18F]-FE-PE2I PET in Parkinson’s disease: discriminative power, testretest reliability and longitudinal validity during early peak and late pseudo-equilibrium. J Cereb Blood Flow Metab. 2020
  Brumberg J, Kerstens V, Cselényi Z, Svenningsson P, Sundgren M, Fazio P, Varrone A
  (See online at https://doi.org/10.1177%2F0271678X20958755)
• Accuracy of 18-F Fluorodeoxyglucose Positron Emission Tomographic/Computed Tomographic Imaging in Primary Staging of Squamous Cell Carcinoma of the Oral Cavity. JAMA Netw Open. 2021; 1:4(4):e217083
  Linz C, Brands RC, Herterich T, Hartmann S, Muller-Richter U, Kubler AC, Haug L, Kertels O, Bley TA, Dierks A, Buck AK, Lapa C, Brumberg J
  (See online at https://doi.org/10.1001/jamanetworkopen.2021.7083)
• Clinical Outcome and Striatal Dopaminergic Function After Shunt Surgery in Patients With Idiopathic Normal Pressure Hydrocephalus. Neurology. 2021
  Todisco M, Zangaglia R, Minafra B, Pisano P, Trifiro G, Bossert I, Pozzi NG, Brumberg J, Ceravolo R, Isaias IU, Fasano A, Pacchetti C
  (See online at https://doi.org/10.1212/WNL.000000000001206)
• Striatal Dopamine Deficit and Motor Impairment in Idiopathic Normal Pressure Hydrocephalus. Mov Disord. 2021; 26:124-132
  Pozzi NG, Brumberg J, Todisco M, Minafra B, Zangaglia R, Bossert I, Trifiro G, Ceravolo R, Vitali P, Isaias IU, Fasano A, Pacchetti C.
  (See online at https://doi.org/10.1002/mds.28366)