PCF11-dependent regulation of transcriptome 3’end mRNP dynamics during neuronal development

• Applicant: Professor Dr. Sven Danckwardt
• Subject Area: General Genetics and Functional Genome Biology
• Term: from 2019 to 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 427452638

• Final Report Year: 2024

No abstract available

Publications

• TREND-DB
  Marini F.; Scherzinger D. & Danckwardt S.
  
• Emerging Roles of RNA 3′-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders. Biomolecules, 10(6), 915.
  Nourse, Jamie; Spada, Stefano & Danckwardt, Sven
  
• TREND-DB—a transcriptome-wide atlas of the dynamic landscape of alternative polyadenylation. Nucleic Acids Research, 49(D1), D243-D253.
  Marini, Federico; Scherzinger, Denise & Danckwardt, Sven
  
• A novel rationale for targeting FXI: Insights from the hemostatic microRNA targetome for emerging anticoagulant strategies. Pharmacology & Therapeutics, 218(c(2021, 2)), 107676.
  Nourse, Jamie & Danckwardt, Sven
  
• TRENDseq—A highly multiplexed high throughput RNA 3′ end sequencing for mapping alternative polyadenylation. Methods in Enzymology (2021), 37-72. Elsevier.
  Ogorodnikov, Anton & Danckwardt, Sven
  
• Post-transcriptional control of haemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders. Cardiovascular Research, 119(8), 1624–1640.
  Danckwardt, Sven; Trégouët, David-Alexandre & Castoldi, Elisabetta