Broadband Cryoprobe for 600 MHz NMR-Spectrometer

• Subject Area: Molecular Chemistry
• Term: Funded in 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 429738312

We apply for funding for a helium cooled NMR probe (cryoprobe) for an existing 600 MHz spectrometer. The new probe will replace an old, irreparably dysfunctional cryoprobe. Compared to to the previously operated cryoprobe, the new system is superior in terms of sensitivity, temperature range and scope of detectable NMR nuclei while reduces acquisition time by a factor of up to 30 relative to the usual ambient temperature probe. In the future, this should allow the recording of NMR spectra of samples which are barely detectable with the aid of the standard technology. These improvements will not only lead to an increase of the turnover of samples for heteronuclear NMR but to tackle particularly challenging problems such as the direct 15N or 29Si-NMR of samples without coupled 1H. The extended temperature range, combined with the extremely high sensitivity at high magnetic field will allow the acquisition of NMR data of high quality at variable temperature. This is inter alia of importance for the investigation of high-molecular polymers in solution which needs to be carried above 120°C. A principal field of application will be the 13C-NMR spectroscopy of paramagnetic compounds. Several important magnetic parameters may be determined NMR spectroscopically based on their temperature dependence. This will give rise to important insights in the field of molecular magnetism. Further applications of the new system will be the determination of kinetic parameters of catalytic reactions, the elucidation of the reaction mechanisms and the structural characterization and investigation of main group element compounds with unsual molecular structures. The focus on the highly sensitive direct detection of heteronucei is unique and complementary to the existing NMR infrastructure of the Heidelberg faculty.

• DFG Programme: Major Research Instrumentation
• Major Instrumentation: Breitband-Cryoprobenkopf für 600 MHz NMR-Spektrometer
• Instrumentation Group: 1740 Hochauflösende NMR-Spektrometer
• Applicant Institution: Ruprecht-Karls-Universität Heidelberg
• Leader: Professor Dr. Lutz H. Gade