T-Zellrezeptor-Gentransfer zur Konstruktion von Cancer-Testis Antigen-spezifischen T-Zellen für die Behandlung von multiplen Myelomen

• Applicants: Professorin Dr. Helga Bernhard; Professor Dr. Wolfgang Uckert
• Subject Area: Hematology, Oncology
• Term: from 2007 to 2010
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 44335118

• Final Report Year: 2013

Final Report Abstract

No abstract available

Publications

• 2009. Allorestricted T lymphocytes with a high avidity T-cell receptor towards NY-ESO-1 have potent anti-tumor activity. Int J Cancer 2/3 125:649-655
  Krönig H, Hofer K, Conrad H, Guilaume P, Müller J, Schiemann M, Lennerz V, Cosma A, Peschel C, Busch DH, Romero P, Bernhard H
  
• 2010. Targeting the epidermal growth factor receptor (HER) family by T cell receptor genemodified T lymphocytes. J Mol Med 88:1113-1121
  Meyerhuber P, Conrad H, Stärck L, Leisegang M, Busch DH, Uckert W, Bernhard H
  
• 2011. FLT3-regulated antigens as targets for leukemia-reactive cytotoxic T lymphocytes. Blood Cancer J 3:e11
  Brackertz B, Conrad H, Daniel J, Kast B, Krönig H, Busch DH, Adamski J, Peschel C, Bernhard H
  
• 2013. NY-ESO-1 antigen-reactive T cell receptors exhibit diverse therapeutic capability. Int J Cancer 132:1360-1367
  Sommermeyer D, Conrad H, Krönig H, Gelfort H, Bernhard H, Uckert W
  (See online at https://doi.org/10.1002/ijc.27792)