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Interaction of macrophages with cell matrix niches in lymphoid organs (A12*)

Subject Area Immunology
Term since 2020
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 194468054
 
Lymphoid follicles within secondary lymphoid organs are anatomically delineated by biological barriers formed by specialized stromal endothelial cells. We previously observed that CD169+ macrophages interact with the stroma in these barriers. We aim to decode the molecular pathways defining these macrophage-stromal cell interactions and their impact in the specific immune responses to blood- and lymph-borne pathogens.
DFG Programme Collaborative Research Centres
Applicant Institution Universität Münster
 
 

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