The noradrenergic system´s contribution to neural resource in aging (A08#)

• Subject Area: Human Cognitive and Systems Neuroscience
• Term: from 2021 to 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 425899996

The integrity of the locus coeruleus (LC)-noradrenergic (NA) system is important in determining late-life cognitive abilities. The proposed project examines whether differences in the integrity of the LC-NA system can explain preserved cognitive functions in so-called ‘SuperAgers’ and whether boosting the LC-NA system offers hidden potential in boosting neural resource in ageing. This will be achieved by increasing NA function pharmacologically as well as by training particular cognitive functions known to recruit the LC-NA system in physiologically healthy older adults.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1436: Neural resources of cognition
• Applicant Institution: Otto-von-Guericke-Universität Magdeburg
• Project Heads: Privatdozent Dr. Matthew Betts, Ph.D.; Professorin Dr. Dorothea Hämmerer