Effects of hippocampal vascularization patterns on the neural resources of MTL neurocognitive circuits (B04)

• Subject Area: Human Cognitive and Systems Neuroscience
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 425899996

The medial temporal lobe (MTL) is crucial for episodic memory formation. MTL integrity is affected by pathology and environmental factors. Hippocampal vascularization could play an additional role. We aim to resolve whether hippocampal vascularization patterns segregate along distinct MTL neurocognitive (meso-scale) circuits. Using advanced modeling technology, we will investigate the relationship between hippocampal vascular supply, MTL pathology, integrity, myeloarchitecture, and subregion-specific cognitive functions. We will test the interaction between cognitive training and hippocampal vascularization on MTL function.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1436: Neural resources of cognition
• Applicant Institution: Otto-von-Guericke-Universität Magdeburg
• Project Heads: Professorin Dr. Esther Kühn, Ph.D.; Professorin Dr. Anne Maass; Professorin Dr. Stefanie Schreiber