Project Details
Projekt
Control of organelle biogenesis by the Lipin switch (A23)
Subject Area
Biochemistry
Term
since 2020
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 278001972
Project A23 will continue to investigate the role of the Lipin switch in the biogenesis of the endoplasmic reticulum and lipid droplets. Specifically, the mechanisms through which individual Lipin family members regulate lipid synthesis and storage will be better defined, improved small-molecule Lipin inhibitors will be developed, and the spatial organization of the Lipin switch at the suborganellar level will be explored. These studies will provide insight into an important regulator of lipid metabolism and provide tools for its manipulation, potentially also for medical application.
DFG Programme
CRC/Transregios
Applicant Institution
Freie Universität Berlin
Project Heads
Professor Dr. Oliver Daumke; Professor Dr. Sebastian Schuck
