Magnetic Particle based Cov-Indicator

• Applicant: Dr. Patrick Vogel
• Subject Area: Medical Physics, Biomedical Technology
• Term: from 2020 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 451692365

In this project, the feasibility of a small and inexpensive measuring devices for the rapid detection of Covid-19 antibodies is investigated (corona rapid test). The approach follows the detection of signal changes of magnetic particles by means of magnetic fields. The magnetic particles are functionalized with specific antigens and show a cross-linking in the presence of antibodies, which results in a strong signal change.The technologies are based on magnetic particle spectroscopy (MPS). However, a higher sensitivity can be achieved by changing the magnetic field configuration (from linear to rotating), which is provided by the so-called rotating drift spectroscopy (RDS).A novel combination of MPS and RDS, the rotating MPS (rMPS) seems to be a promising approach for this application, as it can combine the advantages of both methods.

• DFG Programme: Research Grants
• Co-Investigator: Professor Dr. Volker Christian Behr