Project Details
Projekt
Targeting immune cell dynamics by longitudinal whole-body imaging and mathematical modelling (A05)
Subject Area
Medical Physics, Biomedical Technology
Term
since 2021
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 431460824
We develop strategies for tracking and quantifying (immune) cell populations or even single cells in whole-body PET and PET-MRI studies in mice and humans. This will be achieved through novel acquisition protocols, physical and computational phantom development, mathematical modelling, and mathematical analysis of image reconstruction with novel combinations of PET or MRI measurement operators and temporal regularization paradigms. Particular applications include imaging and tracking of macrophages and neutrophils in hypoxia or arthritis models.
DFG Programme
Collaborative Research Centres
Applicant Institution
Universität Münster
Project Heads
Professor Dr. Klaus Schäfers; Professor Dr. Benedikt Wirth
