Phagocyte responses during apoptotic cell clearance in the resolution of inflammation (C02)

• Subject Area: Immunology
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 431460824

The phagocytosis of apoptotic cells by macrophages is crucial to resolve inflammation and promote tissue repair. We previously observed that resident macrophages in different tissues exert diverse immune responses upon dead cell clearance. We aim to decode the transcriptional and metabolic pathways in macrophages that contribute to the organ-specific immune responses through the phagocytosis of diverse apoptotic cargos.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1450: Multiscale imaging of organ-specific inflammation
• Applicant Institution: Universität Münster
• Project Head: Dr. Noelia Alonso Gonzalez