Reorganisation of the motor system following stroke (C05)

• Subject Area: Cognitive, Systems and Behavioural Neurobiology ; Human Cognitive and Systems Neuroscience
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 431549029

Functional MRI, simultaneous TMS-EEG recordings, and online-TMS interference with focal brain activity will be used as a multimodal readout of premotor and primary motor cortex function in stroke patients suffering from motor deficits. The project will serve to clarify the role of these areas for motor function and recovery of individual patients with different degrees of impairment. Further, individual response profiles of regions in the fronto-parietal cortex will be linked to the effect of neuromodulatory intervention using intermittent theta-burst rTMS, laying the ground for an individualised treatment approach based on the individual functional network pathology at a given time post stroke.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1451: Key mechanisms of motor control in health and disease
• Applicant Institution: Universität zu Köln
• Project Heads: Professor Dr. Gereon Rudolf Fink; Professor Dr. Christian Grefkes-Hermann