Age-dependent airway epithelial determinants of severe human respiratory viral infections (A01)

• Subject Area: Virology
• Term: since 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 492620490

A01 will focus on the link between age-specific cellular differentiation and immune function of the upper respiratory tract epithelium as well as viral entry, replication and spreading. The accessibility of candidate molecular decision points to modification and resulting consequences for the outcome of respiratory viral infections (RVIs), and microbiota-derived environmental cues impacting on the programming of molecular decision points in RVIs will be investigated.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1583: Decisions in Infectious Diseases (DECIDE)
• Applicant Institution: Julius-Maximilians-Universität Würzburg
• Project Heads: Dr. Simone Backes; Professorin Dr. Dorothee Viemann