In silico modelling of spinal cord Regeneration (B01)

• Subject Area: Mechanics
• Term: since 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 460333672

B01 aims to establish a continuum-based computational framework to predict the regeneration of spinal cord tissue after injury or disease. The computational model will capture the temporal and spatial evolution of growth, remodelling, and healing processes. We will specifically focus on mechanics-driven processes that are involved in the regeneration of the spinal cord after traumatic injury and in multiple sclerosis. To calibrate the constitutive models, we will exploit mechanical tests on human and animal spinal cord tissue.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1540: Exploring Brain Mechanics (EBM): Understanding, engineering and exploiting mechanical properties and signals in central nervous system development, physiology and pathology
• Applicant Institution: Friedrich-Alexander-Universität Erlangen-Nürnberg
• Project Heads: Professorin Dr.-Ing. Silvia Budday; Professor Dr.-Ing. Paul Steinmann