Project Details
Yeast mutants with drastically reduced fatty acid synthase activity: molecular background and consequences on cellular protein palmitoylation
Applicant
Professor Dr. Eckhart Schweizer (†)
Subject Area
Biochemistry
Term
from 2001 to 2008
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 5351817
Final Report Year
2008
Final Report Abstract
No abstract available
Publications
- Funktionelle Charakterisierung und selektive Inaktivierung verschiedener Saccharomyces cerevisiae-Gene, die an der Bildung überlanger Fettsäuren beteiligt sind. Dissertation
Heidi Rössler
- Genetische und biochemische Charakterisierung der Fettsäure-Elongase in der Hefe Saccharomyces cerevisiae. Dissertation
Christoph Rieck
- Nachweis und Funktion der Biotinylierung des Aminoacyl-tRNA-Synthetase Cofaktors Arc1p in Saccharomyces cerevisiae. Dissertation
Hyun Soo Kim
- Untersuchungen zur Biochemie und Genetik des Sphingolipid-Stoffwechsels in Saccharomyces cerevisiae. Dissertation
Dirk Zajonc
- Untersuchungen zur Wirkungsweise der ISC1-kodierten Inositolphospho-Sphingolipid Phospholipase C in Saccharomyces cerevisiae. Dissertation
Christian Betz
- Versuche zur affinitätschromatographischen Reinigung, zur Expression und zur funktionellen Charakterisierung der mitochondriellen Acetyl-CoA Karboxylase Hfal in Hefe. Dissertation
Sandra Marthol
- 2002. ISC1-encoded Inositol Phosphosphingolipid Phospholipase C is involved in Na+/Li+ Halotolerance in Saccharomyces cerevisiae. Eur. J. Biochem. 269, 4033-4039
Betz, C., Zajonc, D., Moll, M. and Schweizer, E.
- 2003. Functional Differentiation and Selective Inactivation of Multiple Saccharomyces cerevisiae Genes Involved in Very-long-chain Fatty Acid Synthesis. 2003. Mol. Gen. Genomics 269, 290-298
Roessler, H., Rieck,C., Delong, T,, Hoja, U. and Schweizer, E.
- 2004. HFA1 Encoding an Organelle-specific Acetyl-CoA Carboxylase Controls Mitochondrial Fatty Acid Synthesis in Saccharomyces cerevisiae. J. Biol. Chem. 279, 21779-21786
Hoja, U., Marthol, S., Hofmann, J., Stegner, S., Schulz, R., Meier, S. Greiner, E. and Schweizer, E.
- 2004. Identification of the tRNA Binding Protein Arc1p as a Novel Target of in vivo Biotinylation in Saccharomyces cerevisiae. J. Biol. Chem. 279,42445-42452
Kim, H.S., Hoja, U., Stolz, J., Sauer, G. and Schweizer, E.
- 2004. Microbial Type I Fatty Acid Synthases (FAS) : Major Players in a Network of Cellular FAS Systems. Molec. Biol. Rev. 68, 501- 517
Schweizer, E. and Hofmann, J.
- 2005. Cloning, Expression and Characterization of the Human Mitochondrial ß-Ketoacyl Synthase. J. Biol. Chem. 280, 12422-12429
Zhang, L., Joshi, A.K., Hofmann, J., Schweizer, E. and Smith, S.