Molekulare Analyse von Proteinkomplexen, die an der Signalübertragung zum Aktinzytoskelett beteiligt sind

• Applicant: Professorin Dr. Theresia Stradal
• Subject Area: Cell Biology
• Term: from 2002 to 2008
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5469361

• Final Report Year: 2010

No abstract available

Publications

• (2004) Abi1 is essential for the formation and activation of a WAVE2 signalling complex. Nat Cell Biol., 6, 319-327
  Innocenti, Metello; Zucconi, Adriana; Disanza, Andrea; Frittoli, Emanuela; Areces, Liliana B.; Steffen, Anika; Stradal, Theresia E. B.; Fiore, Pier Paolo Di; Carlier, Marie-France & Scita, Giorgio
  
• (2004) Eps8 controls actinbased motility by capping the barbed ends of actin filaments. Nature Cell Biol., 6, 1180-1188
  Disanza, Andrea; Carlier, Marie-France; Stradal, Theresia E. B.; Didry, Dominique; Frittoli, Emanuela; Confalonieri, Stefano; Croce, Assunta; Wehland, Jurgen; Di Fiore, Pier Paolo & Scita, Giorgio
  
• (2004) Regulation of actin dynamics by WASP and WAVE family proteins. Trends Cell Biol 14, 303-311
  Stradal, Theresia E.B.; Rottner, Klemens; Disanza, Andrea; Confalonieri, Stefano; Innocenti, Metello & Scita, Giorgio
  
• (2005) PREL1 links Ras signalling to actin remodelling via Ena/VASP proteins. FEBS Lett., 579, 455–463
  Jenzora, Andrea; Behrendt, Barbara; Small, J. Victor; Wehland, Jürgen & Stradal, Theresia E.B.
  
• (2005) Aktindynamik und WASP/WAVE-Proteine. Biospektrum, 11(3), 283-286
  Stradal, T.E.B., Wehland, J.
  
• (2005) Vinculin acts as a sensor in lipid regulation of adhesion site turnover. J. Cell Sci., 118, 1461-1472
  Chandrasekar, Indra; Stradal, Theresia E. B.; Holt, Mark R.; Entschladen, Frank; Jockusch, Brigitte M. & Ziegler, Wolfgang H.
  
• (2005). Actin polymerization machinery: the finish line of signaling networks, the starting point of cellular movement. Cell Mol Life Sci., 62, 955-970
  Disanza†, A.; Steffen†, A.; Hertzog†, M.; Frittoli, E.; Rottner, K. & Scita, G.
  
• (2006) Molecular regulation of cytoskeletal rearrangements during T cell signalling. In: Results and Problems in Cell Differentiation (RPCD); Volume: Cell Communication in Nervous and Immune System (eds. B. Schraven & E. Gundelfinger), Springer Verlag, Berlin, 43, pp 219-44
  Stradal, Theresia E. B.; Pusch, Rico & Kliche, Stefanie
  
• (2006) Protein complexes regulating cellular actin assembly. Curr. Op. Cell Biol., 18, 4-10
  Stradal, Theresia EB & Scita, Giorgio
  
• (2006) The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation. Proc. Natl. Acad. Sci. U. S. A., 103(20), 7694-7699
  Schirenbeck, Antje; Arasada, Rajesh; Bretschneider, Till; Stradal, Theresia E. B.; Schleicher, Michael & Faix, Jan
  
• (2007) c-Met is essential for wound healing in the skin. J. Cell Biol., 177(1), 151-162
  Chmielowiec, Jolanta; Borowiak, Malgorzata; Morkel, Markus; Stradal, Theresia; Munz, Barbara; Werner, Sabine; Wehland, Jürgen; Birchmeier, Carmen & Birchmeier, Walter
  
• (2007) RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T- cell-receptor-mediated integrin activation. Mol. Cell. Biol., 27(11), 4070-4081
  Ménasché, Gaël; Kliche, Stefanie; Chen, Emily J. H.; Stradal, Theresia E. B.; Schraven, Burkhart & Koretzky, Gary
  
• (2009) IRSp53 links Tir to EspFU/N-WASP-mediated actin assembly in EHEC pedestal formation. Cell Host Microbe, 5, 244-258
  Weiss, Stefanie M.; Ladwein, Markus; Schmidt, Dorothea; Ehinger, Julia; Lommel, Silvia; Städing, Kai; Beutling, Ulrike; Disanza, Andrea; Frank, Ronald; Jänsch, Lothar; Scita, Giorgio; Gunzer, Florian; Rottner, Klemens & Stradal, Theresia E.B.
  
• (2009). Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis. PLOS Genet., 5(10), e1000675
  Giuliani, Chiara; Troglio, Flavia; Bai, Zhiyong; Patel, Falshruti B.; Zucconi, Adriana; Malabarba, Maria Grazia; Disanza, Andrea; Stradal, Theresia B.; Cassata, Giuseppe; Confalonieri, Stefano; Hardin, Jeffrey D.; Soto, Martha C.; Grant, Barth D. & Scita, Giorgio